Each bearing is independent of the other and they don’t have to be pointing the same direction. However if you need to loosen and change an axle one would certainly want the left side (brake side) to point out towards the tire to make access to the set screws easier. If you have the set screws pointed from the cassette towards the rotor it’ll give you very little room to work.
Conversely, if you CAN make that work, then you might want the removable seals facing such that they are easily removed so you can more easily clean and regrease the bearings.
Whatever works for you.
Think about maintenance, go through a mental dry run of tightening, changing axle and regreasing, then decide what you want to do