Of note is that whether you use RTV type silicone or not, some type of material which acts as a lube during installation of the pipe should be part of the assembly. I have used a silicon lubricant in a tube, bought from NAPA, when not using the high-temp RTV. Important is that the ring grooves should be thoroughly cleaned every time the o-rings are replaced. And, the inside of the pipe which slips over the flange should be very smooth. I use “Scotchbrite” there.
The point is that the o-rings should be tightly compressed between the flange and the pipe. The pipe should not just slip on easily, there has to be a snug fit, otherwise it will leak quickly, whether RTV is used or not. The danger comes in not putting the pipe on squarely during installation. An o-ring which slips partially out of a groove will be cut through, and fail to perform the function for which it was installed in the first place.