I’m not claiming to be an expert but the way I would do it is set the clip in the middle and probably start at 195 main jet and go from there with air screw 1 turn out or so. Then adjust the clip to get the mid throttle you want and tune the main jet by running the motor at full throttle then immediately shutting it down and looking at the plug. That’s the easy way to do it imo and once you get more comfortable with how they are supposed to run you can do it more by feel.
I always have ran redline oil at 25:1 for what its worth
if you google around there is a mikuni manual on how to tune these carbs, if you stay on the rich side they are pretty damn tough motors.